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Environmental persistent pharmaceutical pollutant : ウィキペディア英語版
Environmental persistent pharmaceutical pollutant

The term Environmental persistent pharmaceutical pollutants (EPPP) was first suggested in the nomination in 2010 of pharmaceuticals and environment as an emerging issue in a Strategic Approach to International Chemicals Management (SAICM)〔(Strategic Approach to International Chemicals Management )〕 by the International Society of Doctors for the Environment (ISDE). The occurring problems from EPPPs are in parallel explained under environmental impact of pharmaceuticals and personal care products (PPCP). The European Union summarizes pharmaceutical residues with the potential of contamination of water and soil together with other micropollutants under “priority substances”.〔(DIRECTIVE 2013/39/EU of 12 August 2013 amending Directives 2000/60/EC and 2008/105/EC as regards priority substances in the field of water policy )〕

==Background==
Pharmaceuticals comprise one of the few groups of chemicals that are specifically designed to act on living cells, which presents a special risk when they enter, persist and disseminate in the environment.
With exception for downstream sewage treatment plants, the concentration of pharmaceuticals in water is probably extremely low. However, the effect that the chronic exposure to environmental pharmaceuticals chemicals adds to the effects of other chemicals in the cocktail is still not studied. The different chemicals might be potentiating synergistic effects (1+1=3). An extremely sensitive group in this respect are foetuses.
EPPPs are already found in water all over the world. The diffuse exposure might contribute to
* extinction of species and imbalance of sensible ecosystems, as many EPPPs affect the reproductive systems of for example frogs, fish and mussels;
* genetic, developmental, immune and hormonal health effects to humans and other species, in the same way as e.g. oestrogen-like chemicals;
* development of microbes resistant to antibiotics, as is found in India.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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